When I moved my insulin pump a couple of days ago, I stuck it in my belly fat, and my insulin usage went straight up like 80 units per day. It looks like picking a spot that doesn’t have 31 years of needle scar tissue, along with picking a low fat spot, really reduces the insulin that is needed to do the job. Some young Doc needs to do a study on that….
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This was posted a while ago but I need to make a comment. I was at the dermatologist recently and saw a picture of a cross section of the skin hanging on the wall. I asked where the end of a 9 mm cannula might be in the picture. I wanted to see where the insulin bolus was being deposited. No wonder there is so much variation in insulin activity with different sites. There are all kinds of organelles and even tiny blood capillaries in the area where the insulin can go and be quickly distributed through the body. Then again it may wind up in a big fat cell and go no where fast.
It would be interesting as you said if som young Doc(s) did a study on the deposit, absorption, and distribution of insulin after a bolus. I would be more than happy to volunteer.