Diabetes And Alzheimer’s Disease

There is an interesting article out about a study that was done by Suzanne de la Monte, M.D., that says that insulin resistance can be a factor in Alzheimer’s Disease. The press release on the study is here, but if you read to the bottom of the page, I also found a study that tells you what the cure is… OK, maybe the cure is a little strong, but check it out anyway. (at least those of you who don’t want to get any dumber…)

Growing evidence supports the concept that AD is fundamentally a metabolic syndrome that leads to abnormalities linked to brain insulin and insulin-like growth factor (IGF) resistance. In AD, brain insulin and IGF resistance and deficiencies begin early and worsen with severity of the disease. The rationale behind the progression of the disease is that insulin-resistance dysregulates lipid metabolism and promotes ceramide accumulation, thereby increasing inflammation and lipid metabolism, causing toxic ceramides to accumulate in the brain. The end result is increased stress that threatens the survival and function of neurons in the brain.

Here’s the cure, or at least a tiny little bit of hope… http://www.j-alz.com/press/2012/20120306.html

A team of academic researchers has identified the intracellular mechanisms regulated by vitamin D3 that may help the body clear the brain of amyloid beta, the main component of plaques associated with Alzheimer’s disease.

The article goes on to say that Alzheimer’s looks like it gets worse with lower Vitamin D3, and gets better with higher levels of D3.

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