There is an interesting article out about a study that was done by Suzanne de la Monte, M.D., that says that insulin resistance can be a factor in Alzheimer’s Disease. The press release on the study is here, but if you read to the bottom of the page, I also found a study that tells you what the cure is… OK, maybe the cure is a little strong, but check it out anyway. (at least those of you who don’t want to get any dumber…)
Growing evidence supports the concept that AD is fundamentally a metabolic syndrome that leads to abnormalities linked to brain insulin and insulin-like growth factor (IGF) resistance. In AD, brain insulin and IGF resistance and deficiencies begin early and worsen with severity of the disease. The rationale behind the progression of the disease is that insulin-resistance dysregulates lipid metabolism and promotes ceramide accumulation, thereby increasing inflammation and lipid metabolism, causing toxic ceramides to accumulate in the brain. The end result is increased stress that threatens the survival and function of neurons in the brain.
Here’s the cure, or at least a tiny little bit of hope… http://www.j-alz.com/press/2012/20120306.html
A team of academic researchers has identified the intracellular mechanisms regulated by vitamin D3 that may help the body clear the brain of amyloid beta, the main component of plaques associated with Alzheimer’s disease.
The article goes on to say that Alzheimer’s looks like it gets worse with lower Vitamin D3, and gets better with higher levels of D3.
Seriously, can’t Johnson and Johnson make me some Neosporin with some insulin in suspension in it? The benefits for type1 and type 2 diabetics would be huge.
I’ve always believed that high blood sugars inhibit the healing of wounds, and even went down to Loma Linda in the early 90’s to discuss someone doing a study on suspending insulin in a topical solution so that diabetics could use it for would care. Of course, nothing’s ever come from it, but I’d still like to see someone build this product for diabetics everywhere.
Here are a few studies that back me up on the slow wound healing being tied to high glucose levels.
Here are a couple of articles that say I’m full of crap…
3 parties in the last week. Who the heck is dumb enough to try to diet between Thanksgiving and Christmas? I’ll try this again with everyone else after New Years!
OK, tonight’s Survivor, so I have to sit on the couch and drink Whiskey, so my diet’s going to be screwed for the day. I only had 600 calories today until now, but I just added 8oz of Whiskey to the list at Cronometer, and the calories for the day jumped to 1158.
But, I vacuumed for 1/2 hour today, so maybe I’m not in as much trouble as it seems I am. According to fatburn.com, just watching TV I use 2,297 calories, so I should have lost 1/3 of a pound, even without the vacuuming…
OK, maybe not! After the whiskey I got the munchies and did a number on a bag of popcorn and some chocolate. DAMN!
266 this morning, maybe yesterday wasn’t too bad after all. LOL
I’m not hungry, so fat loading on the dozen oatmeal and raisin cookies last night was a good idea. (Aren’t cookies always a good idea?) My total caloric intake for today was 910 calories, and the extra exercise lowered the net calories to 429 for the day. Here’s a partial screen shot from Cronometer.com.
I was going to take a picture of myself for a before and after HCG diet photo, but I don’t feel like it, so maybe tomorrow.
It’s been a year since I did the last diet, and I’ve gained about 15 lbs over what I weighed at the beginning of the year. So, I broke out the bottle of HCG and the Tony Little Gazelle, and I’m ready to go. LOL
The tools I use to keep track of everything, are the Cronometer.com website, and the fat burner calculator at fatburn.com. At the Cronometer site, you can keep track of all your foods and calories, and input any extra exercising you’ve done by pulling the numbers from fatburn.com. That way you can clearly see your net calorie intake, and graph your weight. You can also keep notes on the site, and if they don’t have the foods you’re currently eating, you can add your own really easy.
This morning I ate 4 little links and drank a pot of coffee… OK, that was a lie, it’s only 10am and I’m up to two pots already. But who cares, water’s good for your, right? (28 calories for 12 cups of black coffee, Cronometer’s drop down list fricken has about every food in America that’s got an FDA label on it. Man it makes keeping track of stuff easy.)
I then did 30 minutes of moderate exercise on the Gazelle, and according to fatburn.com, I burned 481 calories. So, right now I’m at a negative 249 calories. But, when I looked at the chart, 86% of my calories came from fat from the little links, so I’m going to have to dump those things in the future.
I’ll stick a picture up from today, so we can see if I actually look any different as we go along, or so we can see when I cheat, cause cheating on the HCG diet will pack pounds on faster than anything else I’ve ever done.
OK, I might have been a little too quick dumping the Metformin… While I was in Belize, I was only eating 2 means per day, and those were mostly fish and vegetables. And, I wasn’t eating any dairy or wheat, for what that’s worth. (I seem to blow up when I eat anything with wheat in it: from beer to bread, and it seems to take more insulin to knock down the sugars.)
Over the last 2 days, I’ve had 4 blood sugars over 300. That’s really fricken high for me, since I mostly keep under 200. (Of course I know how to fix them really quick, so I can keep down the vascular damage to my eyes etc… Just shoot the insulin directly into a muscle and them massage it for a minute. Shooing your insulin into muscle tissue, and then massaging it, can lower your blood sugar by more than 250 in an hour. (Don’t inject insulin into a muscle unless you really, really need to drop your blood sugar fast, or you can go into insulin shock in under half an hour.))
Another thing that might be causing the high blood sugars is that fact that I haven’t taken my Testosterone in a couple of weeks; and I usually take it every week. When I don’t take my Testosterone on a regular basis, my stomach quits working, and my Gastroparesis takes over.
Gastroparesis makes it so your food moves sporadically through your digestive tract, and when I had the test 20 years ago, my food moved 2 inches in 6 hours… What that means, is that you have lows when you take insulin for the food you just ate, then 8 hours later, you might have a super high blood sugar because the stupid food moved when you weren’t ready for it. That’s one of the things that Metformin actually seems to help with, since it seems to make your food move through your digestive tract in a more regular manner.
When I was in Belize for 2 weeks this month, I forgot to take my Metformin. Metformin is usually given to type 2 diabetics to help with blood sugar regulation and insulin uptake. I take it because I’m insulin resistant, and it’s supposed to help regulate my blood sugars.
But, I actually felt better not taking it. My early morning blood sugars, known as “The Dawn Effect”, didn’t go through the roof like they usually do, and now that I’m back in the states, and still not taking it, my 4am blood sugars are still good.
Anyone have any idea why I was getting high morning blood sugars on Metformin?
You won’t find this in any books, but it’s something I’ve used, and believed in, for 20 years. The more sugar in your blood, the higher the chance of infection in a wound… (OK, that one’s in all the books, but read on.)
So, whenever I get an open sore, that just won’t go away, I either take a needle and inject insulin all around the wound, just under the skin, or I take a waterproof band-aid and put insulin on the pad and stick it on the sore. In my opinion, which of course is the only one that matters, this drops the blood sugar in the affected area, which helps heal the wound faster. (Of course, the logic may be flawed, but it’s what I do, and I think it helps.)
When I thought this up in 1988, I talked to a Doctor at Loma Linda Medical Center and asked him if he knew where I could get a substance like petroleum jelly, that I could mix with insulin to make a topical solution that diabetics could apply to open wounds. I figured the mixture would help protect the wound, while at the same time decreasing healing time by increasing insulin in the area. (My favorite product now is Bag Balm, which I think would make a perfect base, if you could figure out how to mix oil and water…)
OK, the name of the site is Type 1 Forums, so I finally added the forums so that we can have some real discussions about diabetes. I’m sorry I didn’t do it earlier, since I know a bunch of you have stuff you want to takj about, and/or start fights about. LOL